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Warfarin's significantly less potent R-enantiomer is metabolized in part by CYP3A4 (and also CYP1A2 and CYP2C19). Check INR far more regularly if coadministered with inhibitors of such isoenzymes and modify warfarin dose if wanted.Inhibition of platelet aggregation by clopidogrel is solely resulting from an active metabolite. Clopidogrel is metabol
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